Search articles, concepts, and chapters
Peer-reviewed glaucoma literature from Q1 ophthalmology and top medical journals, updated daily.
Jack Phu, Henrietta Wang, Michael Kalloniatis
This study analyzed visual field data, finding the 24-2 test often misses residual central sensitivity better captured by the 10-2 test (Functional Vulnerability Zone). This helps clinicians decide when to use the 10-2 test.
Kazuya Morino, Akira Meguro, Masao Nagasaki, Ikuko N Motoike, Masato Akiyama, Takahisa Kawaguchi, Shogo Numa, Yuki Mori, Shota Yasukura et al.
This study identified new genetic factors for high myopia and found a causal link between high myopia and primary open-angle glaucoma, highlighting potential therapeutic targets and disease mechanisms.
Yichen Xiao, Qinghong Lin, Ziwei Xiang, Xuan Ding, Zhiwei He, Zhirong Zhang, Yu Zhao, Xuejun Wang, Shengtao Liu et al.
A new AI model (MAUnet) accurately segments optic disc/cup, outperforming others. This improves precise cup-to-disc ratio calculation, aiding early glaucoma detection and differentiation from high myopia.
Yoshida Yuto, Fujino Yuri, Michihata Nobuaki, Akagi Ayumu, Koizumi Noriko, Okumura Naoki, Tanito Masaki
This study found moderate ambient humidity over 1-2 weeks reduced IOP, while very high humidity increased IOP, specifically in glaucoma patients, suggesting humidity influences IOP.
Tun Tin A, Tan Nicholas Y Q, Tan Royston K Y, Syn Yamon Thant, Chan Hiok Hong, Yu Qing Chang, Porporato Natalia, Narayanaswamy Arun, Foo Reuben Chao-Ming et al.
This study linked asymmetrical NTG-OSA to side-sleeping, finding reduced optic nerve head blood flow in the lower eye during side-lying, suggesting a positional role in glaucoma progression.
Fujita Asahi, Zebardast Nazlee, Lorch Alice C, Miller Joan W, Friedman David S
This study found that MIGS, trabeculectomy, and tube shunts for secondary glaucoma in young adults had ~50% failure at two years, varying by glaucoma subtype. Outcomes suggest tailored surgical approaches are crucial.
Alam Brendan E R, Young Steven K, Kiyota Yuka, Mullaly Catherine M, Oh Kyung, Agarwal Kanika, Davies Emma C, Liu Catherine, Lin Michael M et al.
This study found that 7mL peribulbar blocks, compared to 4mL, led to significantly higher surgeon satisfaction for eye surgery, while both volumes safely reduced intraocular pressure after massage.
Erol Mehmet, Yuce Berna, Kusbeci Tuncay, Demirtas Atilim Armagan
POAG/OHT eyes have thinner anterior sclera, smaller Schlemm's canal, and shorter scleral spur than healthy eyes. This suggests biomechanical coupling, potentially aiding early diagnosis and prognosis.
Ahmed M Abu El-Asrar, Abeer A Alhazzani, Abdulrahman F AlBloushi, Abdullah Alzubaidi, Priscilla W Gikandi, Sveinn H Hardarson, Einar Stefánsson
This study found that worsening diabetic retinopathy correlates with decreased retinal/optic nerve blood flow and paradoxically higher retinal oxygen saturation, suggesting impaired oxygen utilization in advanced disease.
Tuomas Qvist, Oona Ahokas, Johanna Liinamaa, Ville Saarela
This study found OCT and ultrasound pachymetry are interchangeable for central corneal thickness (CCT) measurement. CCT correlated with IOP and optic nerve health, but not glaucoma, suggesting its role in IOP interpretation.
John Landers, Sean Mullany, Mark M Hassall, Jamie E Craig
A study found a single intravitreal bevacizumab dose during trabeculectomy with MMC improved surgical success and reduced medication needs for 3 years, offering a new adjunct for glaucoma surgery.
Ajay Kolli, Evan Chen, Xinyi Xu, Jenny Lu, Patrick Takla, Jill Liang, Matthew Huh, Yuan Zhao, Jadyn Lee et al.
This study found that typical delayed glaucoma follow-ups were not linked to visual field progression. However, very long delays in patients with worse baseline vision showed an association, suggesting current intervals are often adequate.
Jost B Jonas, Rahul A Jonas, Mukharram M Bikbov, Gyulli M Kazakbaeva, Li Dong, Ya Xing Wang, Songhomitra Panda-Jonas
This study proposes myopic axial elongation is driven by retina-triggered growth of Bruch's membrane in the posterior midperiphery. This offers a new target for myopia prevention by understanding retinal signaling.
Kaiyi Chi, Yiru He, Xin Zuo, Chunran Lai, Jiahui Cao, Yican Ying, Binghua Zhang, Renyu Li, Meilin Chen et al.
This study found accelerated biological aging is linked to increased cataract risk, especially retinal aging, suggesting it could be a target for assessment and intervention.
Suphi Taneri, Anika Förster, Mira Grigat, H Burkhard Dick
Diagonal haptic capture of a 4-haptic IOL for posterior capsule deficiency showed stable long-term fixation, good visual outcomes, and low complications, suggesting a safe alternative for IOL placement.
Victoria Barnett, Christopher Ashton, Lucy Barker
Secondary IOL implantation in children/young adults significantly progressed pre-existing glaucoma (71%) but rarely caused new glaucoma (3%). This highlights careful selection and monitoring for patients with prior glaucoma.
Inês Leal, Aniruddha Agarwal, Meghan Berkenstock, Koh-Hei Sonoda, Emilio Dodds, John H Kempen, Antoine P Brézin, De-Kuang Hwang, Maria Vittoria Cicinelli et al.
Experts developed multimodal imaging guidelines for cytomegalovirus retinitis. They found color fundus photography is primary, while OCT and FFA complement for complications. This provides a framework for optimal CMVR imaging.
Liu Yao-Lin, Tsai Tzu-Hsun, Liu Po-Chen, Lo Wei-Cheng, Lee Yi-An, Ho Tzyy-Chang, Wang Tsing-Hong, Hsiao Chuhsing Kate, Lin Hsien-Ho
This study found diabetic retinopathy causes over half of vision impairment in Taiwanese diabetics, with higher burdens in younger adults, females, and eastern regions, highlighting needs for targeted screening and care.
Kareena Chawla, Prashant D Tailor, Jayanth Sridhar
New technologies like heads-up displays, AI, and robotics enhance ophthalmic surgery ergonomics and efficiency. While promising, more research is needed to prove consistent improvements in long-term patient outcomes and cost-effectiveness.
Andrzej Grzybowski, T Y Alvin Liu, Marko M Popovic, Ally Zhao, Masahiro Miyake, Hidenori Takahashi, Ryo Kawasaki, Mingguang He, Xia Gong et al.
This review found ophthalmic AI device regulations vary globally, creating deployment hurdles. Aligned international standards are crucial for safe, equitable clinical use.
Giorgina E Maxwell, Joshua M Schmidt, Antonia Kolovos, Thi T Nguyen, Katherine Zamora-Alejo, Jonathan B Ruddle, Michael Alex Craig, Mark Walland, Anne M V Brooks et al.
FOXC1 gene duplications were found to be a common, highly penetrant cause of juvenile open-angle glaucoma, suggesting genetic testing for these duplications in JOAG patients.
Siab Medhi, Vienne-Jumeau Aliénor, Romana Marc, Belhadia Chahine, Laurent Erika, Etienne-Julan Maryse, Connes Philippe, Beral Laurence
Adults with sickle cell disease exhibit subclinical optic nerve thinning linked to genotype, retinopathy, and vaso-occlusive events. OCT combining BMO-MRW, RNFL, and GCC can guide risk-stratified surveillance for early detection.