Use of erythropoietin in ophthalmology: a review.
Feizi Sepehr, Alemzadeh-Ansari Mohammadhasan, Karimian Farid, Esfandiari Hamed
AI Summary
This review explored erythropoietin's role in eye health and its potential to treat diverse ocular diseases, including glaucoma, due to its protective effects.
Abstract
Erythropoietin (EPO) is a glycoprotein hormone that regulates hematopoiesis in the human body. The presence of EPO and its receptors in different tissues indicates that this hormone has extramedullary effects in other tissues, including the eye. We focus on the biological roles of this hormone in the development and normal physiologic functions of the eye. Furthermore, we explore the role of EPO in the management of different ocular diseases - including diabetic retinopathy, retinopathy of prematurity, inherited retinal degeneration, branch and central retinal vein occlusion, retinal detachment, traumatic optic neuropathy, optic neuritis, methanol optic neuropathy, nonarteritic anterior ischemic optic neuropathy, glaucoma, and scleral necrosis.
MeSH Terms
Shields Classification
Key Concepts4
The role of erythropoietin (EPO) in the management of various ocular diseases, including diabetic retinopathy, retinopathy of prematurity, inherited retinal degeneration, branch and central retinal vein occlusion, retinal detachment, traumatic optic neuropathy, optic neuritis, methanol optic neuropathy, nonarteritic anterior ischemic optic neuropathy, glaucoma, and scleral necrosis, is explored.
Erythropoietin (EPO) is a glycoprotein hormone that regulates hematopoiesis in the human body.
Erythropoietin (EPO) and its receptors are present in various tissues, indicating extramedullary effects, including in the eye.
The biological roles of erythropoietin (EPO) in the development and normal physiologic functions of the eye are a focus of review.
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