Retinal ganglion cell degeneration in experimental optic atrophy.
AI Summary
Owl monkey studies showed retinal injury causes rapid, progressive ganglion cell loss within weeks, modeling optic atrophy relevant to human glaucoma.
Abstract
By ophthalmoscopic and histopathologic examinations at various intervals after retinal injury, we studied progressive ganglion cell atrophy following retinal photocoagulation in 25 owl monkey eyes. A reduced ganglion cell population was apparent within three to four weeks after the photocoagulation and was maximal by six weeks.
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