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OphthalmologyJuly 198832 citations

Acute retinal necrosis syndrome presenting with papillitis and arcuate neuroretinitis.

Margolis T, Irvine A R, Hoyt W F, Hyman R


AI Summary

This ARN case uniquely presented with arcuate neuroretinitis, a peripapillary nerve fiber layer inflammation, suggesting HSV-2 involvement. This expands ARN's known initial presentation spectrum.

Abstract

Acute retinal necrosis (ARN) syndrome is a diffuse uveitis characterized by a peripheral necrotizing retinitis and retinal vasculitis. The authors document and discuss a case of ARN syndrome that initially presented with remarkable changes in the peripapillary retinal nerve fiber layer that they have termed arcuate neuroretinitis. These changes consisted of a well-defined arcuate band of retinitis paralleling the course of a parafoveal nerve fiber bundle. Evaluation of serial serum antibody titers suggests HSV-2 as a possible causative agent in this unique presentation of ARN syndrome.


MeSH Terms

Acute DiseaseDiagnosis, DifferentialFemaleFluorescein AngiographyFundus OculiHumansInflammationMiddle AgedNecrosisNeuritisPapilledemaRetinaRetinal DiseasesRetinal VesselsRetinitisSyndromeTerminology as TopicUveitis

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