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OphthalmologyOctober 199527 citations

Scleritis after glaucoma filtering surgery with mitomycin C.

Fourman S


AI Summary

This study found scleritis can occur after glaucoma surgery with mitomycin C. Prompt steroid treatment resolves inflammation, preserving surgical success, highlighting a treatable complication.

Abstract

Background

Adjunctive intraoperative mitomycin C increases the success of glaucoma filtering surgery, but also the postoperative complications. This is the first report of scleritis after its use.

Patients: In five patients, scleritis developed 3 to 24 weeks after inferior trabeculectomy with mitomycin C. The onset was characterized by acute pain, redness of the eye, and decreased vision. Three patients had anterior scleritis and two had posterior scleritis. Infection or bleb leakage was not seen in any patient.

Results

All patients responded to a course of topical steroids and oral ibuprofen or prednisone.

Conclusion

Anterior and posterior scleritis may complicate the use of topical mitomycin C during trabeculectomy, Prompt diagnosis and treatment reverses the inflammation, maintaining the success of the surgical procedure.


MeSH Terms

Administration, OralAdministration, TopicalAdultAgedAged, 80 and overAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntibiotics, AntineoplasticChemotherapy, AdjuvantFemaleFiltering SurgeryGlaucomaHumansIbuprofenMaleMiddle AgedMitomycinPrednisolonePrednisoneScleritis

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