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Intravitreal aflibercept injection for macular edema secondary to central retinal vein occlusion: 1-year results from the phase 3 COPERNICUS study.
Brown David M, Heier Jeffrey S, Clark W Lloyd, Boyer David S, Vitti Robert, Berliner Alyson J et al.
Am J OphthalmolMar 20130 citationsRandomized Controlled Trial
Intravitreal aflibercept significantly improved vision in CRVO-related macular edema, with benefits maintained at one year with PRN dosing, offering an effective treatment option.