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Genetic Architecture of Trans-Laminar Cribrosa Pressure Difference and Primary Open-Angle Glaucoma.
Hong In-Shik, Cho Chamlee, Kim Beomsu, Shim Injeong, Lee Yeong Chan, Jung Sang-Hyuk et al.
Invest Ophthalmol Vis SciApr 20260 citationsCohort Study
This study identified genetic factors influencing translaminar cribrosa pressure difference (TLCPD). A high TLCPD genetic risk score significantly predicts primary open-angle glaucoma, highlighting TLCPD's crucial role in glaucoma development beyond IOP.