Costantino Santiago

Sayah Diane N, Descovich Denise, Costantino Santiago, Lesk Mark R

This study found that more rigid eyes have less pulsatile choroidal expansion, suggesting ocular biomechanics resist choroidal blood flow. This interaction is crucial for understanding eye disease pathophysiology.

Dumas Rémy, Lacourse Magaly, Kassem Rabea, Lesk Mark R, Costantino Santiago

This study developed an OCT-based algorithm to quantify hypotony maculopathy by measuring Bruch's membrane deviations. It showed good correlation with expert assessment, offering a valuable tool for tracking disease progression and treatment response.

Solano Marissé Masís, Richer Emmanuelle, Cheriet Farida, Lesk Mark R, Costantino Santiago

This study developed an OCT technique to map pulsatile optic nerve head deformation. It accurately detected physiological changes in healthy subjects, showing promise as a biomarker for optic nerve diseases.

Sayah Diane N, Mazzaferri Javier, Descovich Denise, Costantino Santiago, Lesk Mark R

This study found lower ocular rigidity correlated with greater neuroretinal damage in glaucoma, suggesting ocular biomechanics are important for understanding disease progression.

Sayah Diane N, Szigiato Andrei-Alexandru, Mazzaferri Javier, Descovich Denise, Duval Renaud, Rezende Flavio A et al.

Ocular rigidity strongly predicted acute intraocular pressure spikes after anti-VEGF injections. Measuring ocular rigidity could identify patients at risk for significant post-injection pressure increases.

Singh Kanwarpal, Dion Carolyne, Godin Antoine G, Lorghaba Faezeh, Descovich Denise, Wajszilber Marcelo et al.

This study found glaucoma patients have significantly greater pulsatile movement of the nasal peripapillary retina and increased change in axial distance between retina and optic disc cup, potentially indicating altered biomechanics in glaucoma.