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Deng Xizhi

2 articles in GJC

2 articles in GJC

1.

Maraviroc Prevents Optic Nerve Injury-Induced Retinal Ganglion Cell Apoptosis by Modulating the CCL5/CCR5/CTSS Axis.

Huang Jingqiu, Chang Zhaohui, Liu Lian, Lai Cheng, Deng Xizhi, Jiang Bin et al.

Invest Ophthalmol Vis SciJun 20252 citationsBasic Science

Maraviroc, a CCR5 inhibitor, prevented retinal ganglion cell death and preserved optic nerve function in an injury model by modulating the CCL5/CCR5/CTSS pathway. This suggests a promising neuroprotective strategy for glaucoma.

2.

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition.

Zhang Nan, Zhang Pengyu, Deng Xizhi, Zhu Min, Hu Yixin, Ji Dongxiao et al.

Invest Ophthalmol Vis SciJul 20245 citationsBasic Science

Nicotinamide riboside (NR) was found to mitigate glucocorticoid-induced glaucoma by reducing extracellular matrix deposition and mitochondrial damage in the trabecular meshwork, suggesting NR is a promising therapeutic for GIG.

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