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Genetic, clinical, and biological risk factors associated with optic nerve thinning in sickle cell disease.
Siab Medhi, Vienne-Jumeau Aliénor, Romana Marc, Belhadia Chahine, Laurent Erika, Etienne-Julan Maryse et al.
Eye (Lond)May 20260 citationsCross-Sectional Study
Adults with sickle cell disease exhibit subclinical optic nerve thinning linked to genotype, retinopathy, and vaso-occlusive events. OCT combining BMO-MRW, RNFL, and GCC can guide risk-stratified surveillance for early detection.