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Ganglion cell loss in relation to visual disability in multiple sclerosis.
Walter Scott D, Ishikawa Hiroshi, Galetta Kristin M, Sakai Reiko E, Feller Daniel J, Henderson Sam B et al.
OphthalmologyJun 2012236 citationsCross-Sectional Study
This study found that ganglion cell loss (GCL+IPL thinning) in MS patients, especially after optic neuritis, strongly correlates with worse visual function and quality of life, making it a key disease marker.