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Expression of nitrotyrosine and oxidative consequences in the trabecular meshwork of patients with primary open-angle glaucoma.
Fernández-Durango Raquel, Fernández-Martínez Amalia, García-Feijoo Julián, Castillo Alfredo, de la Casa José Martínez, García-Bueno Borja et al.
Invest Ophthalmol Vis SciJun 200856 citationsBasic Science
This study found increased iNOS and nitrotyrosine in POAG trabecular meshwork, correlating with visual field loss. This suggests oxidative stress contributes to TM damage and glaucoma progression.