Freund K Bailey

McLeod D Scott, Bhutto Imran A, Messinger Jeffrey D, Berlin Andreas, Grebe Rhonda, Bijon Jacques et al.

This case study of geographic atrophy found choroidal thickening and large vessels coexisted with severe choriocapillaris degeneration and neovascularization, suggesting structural enlargement doesn't prevent choriocapillaris failure and ischemia.

Faes Livia, Freund K Bailey

Bressler Neil M, Freund K Bailey, Bakri Sophie J, Kim Judy E, Ferrara Daniela, Brittain Christopher et al.

Repeated 0.1mL intravitreous lampalizumab injections for geographic atrophy were studied. Key finding: No significant IOP increase or higher glaucoma/ocular hypertension rates than sham over one year. Clinical relevance: Supports low IOP risk for larger injection volumes.

Wang Xiaofei, Chang Stanley, Grinband Jack, Yannuzzi Lawrence A, Freund K Bailey, Hoang Quan V et al.

MRI showed highly myopic eyes have less optic nerve tortuosity, suggesting higher traction forces during eye movements before myopia onset. This links eye movements to axial elongation, informing glaucoma risk in myopia.

Ledesma-Gil Gerardo, Yannuzzi Lawrence A, Freund K Bailey, Mainster Martin A

Baumal Caroline R, Spaide Richard F, Vajzovic Lejla, Freund K Bailey, Walter Scott D, John Vishak et al.

Brolucizumab injections for AMD can cause severe retinal vasculitis and intraocular inflammation, leading to significant vision loss from retinal artery occlusion. Clinicians need high suspicion for prompt diagnosis.

Leong Belinda C S, Fragiotta Serena, Kaden Talia R, Freund K Bailey, Zweifel Sandrine, Engelbert Michael

OCT revealed age-related connections between vitreous structures (bursa, fissures, cisterns) and their close relationship to retinal vessels. This enhances understanding of vitreous anatomy relevant to vitreoretinal disease.

Kaden Talia R, Freund K Bailey, Engelbert Michael

Mehta Nitish, Lavinsky Fabio, Gattoussi Sarra, Seiler Michael, Wald Kenneth J, Ishikawa Hiroshi et al.

In acute CRVO, increased ganglion cell layer reflectivity and its heterogeneity at one month predict worse 12-month visual outcomes, potentially offering a clinical prognostic tool.

Pang Claudine E, Mrejen Sarah, Hoang Quan V, Sorenson John A, Freund K Bailey

This study found 32-gauge needles for intravitreal injections cause less post-injection reflux but higher immediate IOP spikes than 30-gauge needles, impacting patient safety.

Freund K Bailey, Hoang Quan V, Saroj Namrata, Thompson Desmond

Aflibercept consistently caused less intraocular pressure elevation than ranibizumab in NVAMD patients, suggesting a lower glaucoma risk with aflibercept, which is clinically important for long-term treatment.

Goldberg Naomi, Freund K Bailey

Hoang Quan V, Tsuang Angela J, Gelman Rony, Mendonca Luis S, Della Torre Kara E, Jung Jesse J et al.

This study found more anti-VEGF injections for nAMD significantly increase the risk of sustained intraocular pressure elevation, highlighting the need for vigilant IOP monitoring with long-term treatment.

Tseng Joseph J, Vance Sushma K, Della Torre Kara E, Mendonca Luis S, Cooney Michael J, Klancnik James M et al.

Long-term anti-VEGF therapy for nAMD can cause sustained, significant IOP elevation requiring treatment, even after many prior uneventful injections, necessitating clinical awareness.

Hoang Quan V, Mendonca Luis S, Della Torre Kara E, Jung Jesse J, Tsuang Angela J, Freund K Bailey

This study found more anti-VEGF injections for wet AMD significantly increase the risk of sustained intraocular pressure elevation, highlighting the need for vigilant IOP monitoring in these patients.

Imamura Yutaka, Zweifel Sandrine A, Fujiwara Takamitsu, Freund K Bailey, Spaide Richard F

High-resolution OCT revealed diverse intraretinal and subretinal fluid patterns in optic pit maculopathy, most commonly in the outer nuclear layer, with outer layer holes being uncommon.

Spaide Richard F, Koizumi Hideki, Freund K Bailey

This study found photoreceptor outer segment defects on OCT explain blind spot enlargement in AZOOR-complex diseases, and these defects can improve.

Klais Christina M, Eandi Chiara M, Ober Michael D, Sorenson John A, Sadeghi Sara N, Freund K Bailey et al.

Anecortave acetate for retinal angiomatous proliferation reduced fluid but failed to inhibit neovascularization, causing vision loss. This suggests it's ineffective alone, requiring combination therapy.

Sawa Miki, Ober Michael D, Freund K Bailey, Spaide Richard F

Fundus autofluorescence in PXE patients revealed widespread RPE disturbance and atrophy, often beyond other imaging, suggesting its role in PXE-related vision loss.