Green W R

Kim S Y, Sadda S, Humayun M S, de Juan E, Melia B M, Green W R

This study found geographic atrophy causes severe outer nuclear layer and ganglion cell loss, but preserves inner nuclear layer cells, suggesting potential for vision restoration therapies targeting outer retinal function.

Kim S Y, Sadda S, Pearlman J, Humayun M S, de Juan E, Melia B M et al.

This study found disciform AMD causes significant photoreceptor loss, suggesting outer nuclear layer replacement therapies could be viable for patients.

Equi R A, Green W R

This case reports endogenous *Serratia marcescens* endophthalmitis presenting with a novel "dark hypopyon," a rare finding previously linked to melanoma or *Listeria*, which can aid diagnosis.

Wollensak G, Perlman E J, Green W R

Researchers successfully used FISH to identify the sex of individual cells in human eye tissues. This allows distinguishing host from donor cells in sex-mismatched corneal, RPE, or neuroretinal transplants.

Pollack A L, McDonald H R, Ai E, Green W R, Halpern L S, Jampol L M et al.

This study found sympathetic ophthalmia can occur after pars plana vitrectomy without trauma, presenting diversely. Atypical uveitis post-vitrectomy warrants SO consideration, as immunosuppression can improve vision.

Hayashi N, Geraghty M T, Green W R

Ocular histopathology in Leigh's syndrome (T 8993-G mutation) revealed retinal nerve fiber/ganglion cell thinning and widespread mitochondrial abnormalities. This highlights mitochondrial dysfunction's role in optic neuropathy in such patients.

Bullock J D, Warwar R E, Green W R

This study investigated ocular explosions from periocular anesthetic injections, finding high-pressure injection causes globe rupture, often unrecognized. Prevention involves blunt needles, larger syringes, aspiration, and vigilance to avoid this devastating injury.

Schneider S, Greven C M, Green W R

Laser treatment for extrafoveal CNV in ARMD obliterated the target, but histology revealed 11 new, subclinical CNV areas, highlighting the disease's widespread nature and potential for recurrence.

Park J K, Palexas G N, Streeten B W, Green W R

This study found familial erythrophagocytic lymphohistiocytosis (FEL) causes widespread ocular inflammation, especially in the optic nerve and choroid, highlighting eye involvement as part of this severe systemic disease.

Magnante D O, Bullock J D, Green W R

This study showed peribulbar injection can cause globe rupture and lens extrusion in eye bank eyes, highlighting the potential for devastating complications from anesthetic injection pressure.

Jakobs E M, Adelberg D A, Lewis J M, Trpis M, Green W R

This case showed ophthalmomyiasis interna posterior causing optic atrophy despite larval removal, highlighting early intervention to prevent permanent vision loss.

Küchle M, Vinores S A, Mahlow J, Green W R

This study found pseudoexfoliation syndrome significantly impairs the blood-aqueous barrier, primarily at the iris and less so at the ciliary body, contributing to inflammation and glaucoma.

Kerrison J B, Howell N, Miller N R, Hirst L, Green W R

This LHON study found calcium-rich inclusions within retinal ganglion cells, suggesting mitochondrial dysfunction leads to calcification and optic nerve atrophy. This offers insight into LHON's pathology.

Kerrison J B, Flynn T, Green W R

This study found MS patients often have retinal nerve/ganglion cell atrophy, and surprisingly frequent uveitis and retinal phlebitis, highlighting ocular inflammation as a key MS manifestation.

Eliott D, O'Brien T P, Green W R, Jampel H D, Goldberg M F

This study found *Listeria monocytogenes* endophthalmitis can cause dark hypopyon and high eye pressure. These signs, even in healthy patients, may indicate this rare, severe infection.

Grossniklaus H E, Green W R

This study of 308 myopic eyes found optic nerve changes and posterior staphyloma were most common. These findings highlight diverse structural pathology in advanced myopia, guiding clinical management and understanding disease progression.

Lopez P F, Green W R

This review explored peripapillary subretinal neovascularization, highlighting its distinct features, diverse disease associations, and impact on prognosis and management, crucial for understanding this optic nerve-related condition.

Nawa Y, Jaques J D, Miller N R, Palermo R A, Green W R

A 67-year-old developed total blindness from bilateral optic nerve infarction after neck surgery and hypotension, highlighting severe visual risk from perioperative hypoperfusion.

Schatz H, Green W R, Talamo J H, Hoyt W F, Johnson R N, McDonald H R

This case study of optic nerve meningioma showed ophthalmoscopic collaterals are true retinal-to-choroidal venous bypass channels, some connecting via a subretinal neovascular membrane, clarifying their anatomical origin.

Guyer D R, Green W R, Schachat A P, Bastacky S, Miller N R

A lymphoma patient developed bilateral vision loss from optic nerve infiltration and retinal vessel occlusions (with bacteria), demonstrating lymphoma's direct, therapy-resistant ocular damage.

Iwamoto M, Nawa Y, Maumenee I H, Young-Ramsaran J, Matalon R, Green W R

Morquio syndrome (MPS IVA) eyes showed mucopolysaccharide deposits primarily in the cornea and trabecular meshwork, explaining corneal clouding and potential glaucoma risk from outflow obstruction.

Quigley H A, Dunkelberger G R, Green W R

This study found that significant retinal ganglion cell loss (20-40%) correlates with even mild visual field sensitivity decline (5-10dB) in glaucoma, indicating that visual field tests detect substantial neuronal damage.

el Baba F, Hagler W S, De la Cruz A, Green W R

A choroidal melanoma caused intractable glaucoma from extensive pigment dispersion, highlighting the diagnostic challenge and severe complications of this rare presentation.

Quigley H A, Dunkelberger G R, Green W R

Chronic glaucoma preferentially damages larger optic nerve fibers, leading to substantial nerve loss before visual field defects appear, highlighting a selective vulnerability mechanism.

Lynch M G, Quigley H A, Green W R, Pollack I P, Robin A L

Nd:YAG laser capsulotomy in monkeys decreased outflow facility due to debris, even without IOP rise. This suggests debris can impair outflow, explaining human post-laser IOP spikes.