Guo Wenyi

Wu Yue, Peng Cheng, Huang Lulu, Xu Li, Ding Xuming, Liu Yixin et al.

This study found the GNAQ R183Q mutation in all SWS glaucoma scleral tissue, suggesting it drives episcleral vessel abnormalities via ERK/JNK, offering diagnostic/therapeutic targets for SWS glaucoma.

Wu Yue, Peng Cheng, Ding Xuming, Zeng Changjuan, Cui Chang, Xu Li et al.

This study found young SWS patients with multiple episcleral hemangiomas (MEVAN) had significantly worse trabeculotomy outcomes than those with simple patterns (SEVAN), highlighting vascular patterns' prognostic value.

Wu Yue, Yu Rujing, Chen Di, Xu Li, Zhu Li, Li Mao et al.

Early trabeculotomy for infant SWS glaucoma showed good intermediate-term success and safety, with better outcomes linked to early diagnosis. Higher preoperative IOP increased failure risk.

Yang Qiang, Cho Kin-Sang, Chen Huihui, Yu Dekuang, Wang Wan-Heng, Luo Gang et al.

This mouse model of glaucoma (microbead-induced OHT) selectively responded to aqueous production suppressants, but not outflow drugs, making it useful for screening new therapies targeting aqueous humor production.

Li Mao, Wang Min, Guo Wenyi, Wang Jiajian, Sun Xinghuai

This meta-analysis found caffeine did not affect IOP in normal individuals, but significantly increased IOP in glaucoma/OHT patients, suggesting caution for these patients.

Yu Dao-Yi, Morgan William H, Sun Xinghuai, Su Er-Ning, Cringle Stephen J, Yu Paula K et al.

This review highlights the conjunctiva's critical role in glaucoma surgery success, finding that minimizing surgical trauma and promoting conjunctival drainage pathways (especially lymphatic) are key to long-term intraocular pressure reduction.

Kong Xiangmei, Chen Xueli, Sun Xinghuai, Xiao Ming, Zuo Lei, Guo Wenyi