Brimonidine 0.2% versus dorzolamide 2% each given three times daily to reduce intraocular pressure.
Stewart W C, Sharpe E D, Harbin T S, Pastor S A, Day D G, Holmes K T et al.
This study found brimonidine and dorzolamide provided similar IOP reduction in glaucoma/ocular hypertension, but dorzolamide caused more stinging and brimonidine more itching, indicating comparable efficacy with different side effect profiles.