Higa Kazunari

Kanda Takahiro, Ibrahim Osama M A, Mori-Ogiwara Yurina, Yagi-Yaguchi Yukari, Higa Kazunari, Kasamatsu Hirotsugu et al.

Intracellular dark spots (IDES) after corneal transplant (PK) predict significant endothelial cell loss and graft failure, suggesting IDES may be a crucial prognostic biomarker.

Mori-Ogiwara Yurina, Yagi-Yaguchi Yukari, Ibrahim Osama, Higa Kazunari, Kasamatsu Hirotsugu, Kanda Takahiro et al.

Intracellular dark spots after DSAEK correlate with increased endothelial cell loss and failure, especially with glaucoma, iris damage, or non-Fuchs' dystrophy, indicating a higher risk for graft complications.

Kusano Yuki, Yamaguchi Takefumi, Nishisako Sota, Matsumura Takehiro, Fukui Masaki, Higa Kazunari et al.

This study found high preoperative aqueous protein and specific cytokine levels predict peripheral anterior synechiae progression after DSAEK, indicating chronic inflammation contributes to glaucoma risk.

Tomida Daisuke, Yagi-Yaguchi Yukari, Higa Kazunari, Satake Yoshiyuki, Shimazaki Jun, Yamaguchi Takefumi

This study found tear and aqueous humor cytokine levels correlate only in bullous keratopathy, suggesting tears may reflect intraocular inflammation in these patients.

Yazu Hiroyuki, Yamaguchi Takefumi, Aketa Naohiko, Higa Kazunari, Suzuki Terumasa, Yagi-Yaguchi Yukari et al.

Higher preoperative aqueous inflammatory cytokines (IL-17A, MCP-1, IFN-γ, E-selectin, sICAM-1) predict greater endothelial cell loss after DSAEK, suggesting inflammation impacts graft survival.

Aketa Naohiko, Yamaguchi Takefumi, Asato Teru, Yagi-Yaguchi Yukari, Suzuki Terumasa, Higa Kazunari et al.

This study found chronic ocular surface diseases elevate specific aqueous humor cytokines, indicating persistent inflammation that could impact intraocular surgery outcomes or glaucoma management.

Yagi-Yaguchi Yukari, Yamaguchi Takefumi, Higa Kazunari, Suzuki Terumasa, Yazu Hiroyuki, Aketa Naohiko et al.

Preoperative aqueous humor inflammation (IL-10, MCP-1, IFN-γ) predicts lower corneal endothelial cell density after penetrating keratoplasty, indicating potential for identifying high-risk patients.

Aketa Naohiko, Yamaguchi Takefumi, Suzuki Terumasa, Higa Kazunari, Yagi-Yaguchi Yukari, Satake Yoshiyuki et al.

Iris damage correlates with elevated aqueous humor inflammatory cytokines, indicating localized inflammation. This suggests iris health impacts the ocular inflammatory environment, potentially influencing glaucoma management.

Yamaguchi Takefumi, Higa Kazunari, Suzuki Terumasa, Nakayama Naohiko, Yagi-Yaguchi Yukari, Dogru Murat et al.

Aqueous humor cytokine levels are elevated in bullous keratopathy and low endothelial cell density eyes, suggesting subclinical inflammation may drive endothelial cell loss.