Jonas Rahul A

Jonas Jost B, Jonas Rahul A, Bikbov Mukharram M, Kazakbaeva Gyulli M, Iakupova Ellina M, Milea Dan et al.

Ocular and systemic factors significantly influence measured IOP. Correcting for these determinants reveals a wide "normal" IOP range (e.g., true 21mmHg measures 11-29mmHg), crucial for accurate glaucoma diagnosis and management.

Jonas Jost B, Panda-Jonas Songhomitra, Xu Jie, Jonas Rahul A, Wang Ya Xing

Highly myopic eyes show progressive ONH/macular changes in over 75% of cases over 10 years, linked to axial length and age. This highlights dynamic retinopathy and the need for long-term monitoring to manage complications.

Jonas Jost B, Bikbov Mukharram M, Kazakbaeva Gyulli M, Wang Ya Xing, Nangia Vinay, Milea Dan et al.

This study found high myopia is linked to significant rates of non-glaucomatous and glaucomatous-like optic neuropathies, often with normal IOP, emphasizing diagnostic challenges and the need for careful monitoring.

Jonas Jost B, Jonas Rahul A, Panda-Jonas Songhomitra

This review detailed how axial myopia causes specific structural changes in the optic nerve and macula, including Bruch's membrane shifts and choroidal thinning, increasing glaucoma and macular degeneration risk with longer axial length.

Jonas Jost B, Panda-Jonas Songhomitra, Milea Dan, Lamirel Cédric, Xu Jie, Jonas Rahul A et al.

This study found peripapillary hyperreflective ovoid mass-like structures (PHOMS) are rare (1.6%) in adults, mainly linked to smaller optic discs, and don't indicate optic nerve damage or visual function loss.

Jonas Jost B, Panda-Jonas Songhomitra, Mehta Jodhbir S, Jonas Rahul A

This study found Descemet's membrane is firmly connected to surrounding structures, forming a continuous anatomical unit from the cornea to the optic disc. This highlights the interconnectedness of ocular structures relevant to glaucoma.

Jonas Jost B, Panda-Jonas Songhomitra, Dong Li, Jonas Rahul A

This review detailed myopia's anatomical features, finding specific Bruch's membrane defects and subretinal proliferation linked to severe myopic maculopathy, and distinct parapapillary zones, crucial for differentiating myopic from glaucomatous changes.

Jonas Jost B, Jonas Rahul A, Jonas Shefali B, Panda-Jonas Songhomitra

This study found that in highly myopic eyes, a large optic disk, large parapapillary delta zone, and long axial length can serve as screening criteria for glaucomatous optic neuropathy.

Jonas Jost B, Panda-Jonas Songhomitra, Jonas Rahul A

This study histologically compared macular and parapapillary drusen, finding parapapillary drusen were taller with thicker Bruch's membrane and higher RPE cell density, suggesting regional differences in drusen formation.

Wang Ya Xing, Wang Qian, Jonas Rahul A, Jonas Jost B

This study found a 3.0% PAD prevalence in Chinese adults, linked to older age, diabetes, and retinal vein occlusions, but not glaucoma or other major eye diseases, suggesting limited direct ophthalmic relevance.

Jonas Jost B, Jonas Rahul A, Xu Jie, Wang Ya Xing

This study found myopic macular degeneration (MMD) was the leading cause of vision loss in highly myopic eyes, but optic neuropathy significantly contributed, especially in extreme myopia, highlighting diverse causes needing careful assessment.

Jonas Jost B, Jonas Rahul A, Jonas Shefali B, Panda-Jonas Songhomitra

This study found that in glaucoma and high myopia, choriocapillaris and retinal layers extend further into the parapapillary beta zone, impacting structural assessment.

Jonas Jost B, Jonas Rahul A, Jonas Shefali B, Panda-Jonas Songhomitra

This study linked parapapillary RPE-drusen to shorter axial length and distinct parapapillary zone features. These drusen may help differentiate glaucomatous from myopic beta zone changes.

Jonas Jost B, Jonas Rahul A, Jonas Shefali B, Panda-Jonas Songhomitra

This study found glaucomatous and myopic beta zones differ histologically, suggesting distinct origins. This helps differentiate glaucoma from myopia based on parapapillary changes.

Jonas Jost B, Jonas Rahul A, Bikbov Mukharram M, Wang Ya Xing, Panda-Jonas Songhomitra

Myopia causes diverse structural changes, including retinal thinning, choroidal/scleral thinning, and optic disc remodeling. These changes, potentially driven by Bruch's membrane enlargement, explain various myopic complications, aiding clinical understanding.

Panda-Jonas Songhomitra, Auffarth Gerd U, Jonas Jost B, Jonas Rahul A

This study found that both the retina and ciliary body elongate with increasing eye diameter. This stretching may contribute to optic nerve damage and maculoschisis in highly myopic eyes.

Jonas Jost B, Yan Yan Ni, Zhang Qi, Zhang Qing, Wei Wen Bin, Jonas Rahul A et al.

This study found that thinner RNFL in longer eyes is linked to a longer disc-fovea distance and larger parapapillary gamma zone, suggesting nerve fiber stretching/thinning in these eyes.

Jonas Jost B, Dong Li, Da Chen Shi, Neumaier Michael, Findeisen Peter, Panda-Jonas Songhomitra et al.

This study found intraocular EGF is significantly higher in highly myopic eyes, suggesting EGF may contribute to axial elongation and myopic maculopathy, warranting further investigation into its role in myopia pathogenesis.

Zhang Qing, Xu Liang, Zhao Liang, Jonas Rahul A, Wang Ya Xing, Jonas Jost B

This study found healthy retinal nerve fiber layer peaks vary with age, axial length, gender, and parapapillary anatomy. These factors are crucial for accurate glaucoma diagnosis using OCT.

Jonas Rahul A, Brandt Camilla F, Zhang Qi, Wang Ya X, Jonas Jost B

This study found that a wider inferior parapapillary gamma zone is associated with a more inferior fovea location, suggesting Bruch's membrane shift. This aids understanding of optic disc anatomy.

Jonas Rahul A, Holbach Leonard

This study found peripapillary choroidal tissue remodels with eye length, while peripapillary scleral tissue thickness correlates with glaucoma. These findings are relevant for understanding optic nerve head biomechanics and glaucoma development.

Jonas Jost B, Wang Ya Xing, Zhang Qi, Fan Yuan Yuan, Xu Liang, Wei Wen Bin et al.

This study found that larger parapapillary gamma zones are linked to axial elongation and optic disc rotation, which stretches the temporal peripapillary scleral flange. This explains PPGZ development in myopia.

Jonas Jost B, Jonas Rahul A, Neumaier Michael, Findeisen Peter

This study found numerous inflammatory cytokines, particularly ICAM-1, are elevated in diabetic macular edema and correlate with its severity, suggesting potential therapeutic targets.

Jonas Jost B, Jonas Shefali B, Jonas Rahul A, Holbach Leonard, Panda-Jonas Songhomitra

Highly myopic eyes show an elongated, thinned parapapillary scleral flange and absent Bruch's membrane/choroid, potentially explaining increased glaucoma susceptibility due to altered optic nerve head biomechanics.