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3 articles in GJC
Chang-Wolf Jennifer M, Kinzy Tyler G, Driessen Sjoerd J, Cruz Lauren A, Iyengar Sudha K, Peachey Neal S et al.
Existing glaucoma polygenic risk scores (PRSs) showed lower predictive accuracy in African-ancestry populations compared to European-ancestry groups, highlighting the need for tailored risk models for diverse populations.
Aboobakar Inas F, Kinzy Tyler G, Zhao Yan, Fan Baojian, Pasquale Louis R, Qassim Ayub et al.
Studying TXNRD2/ME3 genetic risk scores in POAG, researchers found higher scores linked to increased treated IOP and paracentral visual field loss, suggesting these genes influence specific glaucoma phenotypes.
Waksmunski Andrea R, Kinzy Tyler G, Cruz Lauren A, Nealon Cari L, Halladay Christopher W, Simpson Piana et al.
A 127-variant genetic risk score for glaucoma performed differently in European vs. African veterans, highlighting the need for diverse genetic data to equitably predict glaucoma risk and treatment needs.
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