Kirwan James F

King Anthony J, Hudson Jemma, Azuara-Blanco Augusto, Kirwan James F, Goyal Saurabh, Lim Kin Sheng et al.

Socioeconomic status correlated with worse baseline visual function and later diagnosis in advanced glaucoma patients, but did not affect treatment success at 24 months, suggesting equitable treatment outcomes regardless of SES.

Holland Lee Joseph, Kirwan James F, Mercieca Karl J

UK glaucoma specialists reduced trabeculectomies during COVID-19, favoring alternatives like laser and drainage devices due to fewer postoperative visits, despite trabeculectomy remaining the overall preference.

Qassim Ayub, Souzeau Emmanuelle, Siggs Owen M, Hassall Mark M, Han Xikun, Griffiths Helen L et al.

This study found that a polygenic risk score for intraocular pressure predicts higher maximum IOP, earlier glaucoma diagnosis, more severe disease requiring surgery, and more affected family members.

Enoch Jamie, Jones Lee, Taylor Deanna J, Bronze Carol, Kirwan James F, Jones Pete R et al.

This review found glaucoma significantly impairs low-light vision, glare tolerance, and dark adaptation, impacting quality of life even in early stages, despite limited performance differences in daily tasks.

Kotecha Aachal, Longstaff Simon, Azuara-Blanco Augusto, Kirwan James F, Morgan James Edwards, Spencer Anne Fiona et al.

A Delphi study established consensus standards for UK glaucoma virtual clinics, covering patient groups, testing, staffing, and governance, providing a guide for service implementation.

Kirwan James F, Lockwood Alastair J, Shah Peter, Macleod Alex, Broadway David C, King Anthony J et al.

This UK study found trabeculectomy provides good IOP control with low complication rates, but requires intensive postoperative care for optimal outcomes.

Ramdas Wishal D, van Koolwijk Leonieke M E, Cree Angela J, Janssens A Cecile J W, Amin Najaf, de Jong Paulus T V M et al.

Studying old and new genetic variants in open-angle glaucoma (OAG), researchers found new variants significantly increase OAG risk. Individuals with many risk alleles had a ~3-fold increased risk, improving predictive accuracy.

Kirwan James F, Cousens Simon, Venter Lynette, Cook Colin, Stulting Andries, Roux Paul et al.

Beta radiation significantly improved glaucoma surgery success by reducing failure rates, but increased the risk of cataract development, offering a trade-off for patients.

Rotchford Alan P, Kirwan James F, Muller Michael A, Johnson Gordon J, Roux Paul

This South African study found high glaucoma prevalence (5.3%), mainly undiagnosed POAG, causing significant blindness. This highlights an urgent need for screening and treatment in similar populations.

Kirwan James F, Nightingale Julia A, Bunce Catey, Wormald Richard

Kirwan James F, Shah Peter, Khaw Peng T

Repeated cyclodiode effectively lowers IOP in refractory pediatric glaucoma, though success is lower and less sustained than in adults. It's a valuable temporizing or adjunct treatment with fewer severe adverse effects.