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Early Gene Expression Profile in Retinal Ganglion Cell Layer After Optic Nerve Crush in Mice.
Ueno Satoru, Yoneshige Azusa, Koriyama Yoshiki, Hagiyama Man, Shimomura Yoshikazu, Ito Akihiko
Invest Ophthalmol Vis SciJan 20180 citationsBasic Science
Mouse optic nerve crush revealed early activation of apoptotic genes, including Atf3, Lcn2, and Tnfrsf12a, in retinal ganglion cells. These genes may be crucial targets for glaucoma neuroprotection.