Marmor Michael F

Marmor Michael F

Marmor Michael F, Ahn Seong Joon, Ehlers Justis P, Melles Ronald B, Mieler William F, Sarraf David et al.

This revised report updates HCQ retinopathy screening, emphasizing OCT/FAF as primary tools, identifying new risk factors, and noting diverse toxicity patterns, enhancing early detection and management.

Melles Ronald B, Marmor Michael F

This study found rapid macular thinning, detectable by OCT, can precede conventional hydroxychloroquine toxicity signs by years, offering an earlier indicator for clinical intervention.

Marmor Michael F, Kellner Ulrich, Lai Timothy Y Y, Melles Ronald B, Mieler William F

Updated guidelines recommend hydroxychloroquine dosing ≤5mg/kg real weight, annual screening after 5 years using OCT/visual fields, and highlight dose/duration as key risk factors for irreversible retinopathy.

Leung Loh-Shan B, Neal Joel W, Wakelee Heather A, Sequist Lecia V, Marmor Michael F

High-dose hydroxychloroquine for cancer caused rapid retinal toxicity (1-2 years), detectable by advanced imaging before symptoms. This highlights the need for sensitive retinal screening in high-dose HCQ trials.

Lee Dong Hoon, Melles Ronald B, Joe Soo Geun, Lee Joo Yong, Kim June-Gone, Lee Chang-Keun et al.

This study found pericentral hydroxychloroquine retinopathy was predominant in Korean patients, not the classic pattern, suggesting new screening approaches are needed for Asian patients.

Melles Ronald B, Marmor Michael F

This study found hydroxychloroquine retinopathy can be pericentral, not just parafoveal, especially in Asian patients, suggesting screening needs to adapt for these distinct patterns.

Marmor Michael F, Chien Fred Y, Johnson Mark W

Comparing red vs. white 10-2 visual fields for hydroxychloroquine retinopathy, red targets were more sensitive for early damage, but white fields with pattern deviation plots were more consistent and should be standard for screening.

Leng Theodore, Wu Peggy, Mehenti Neville Z, Bent Stacey F, Marmor Michael F, Blumenkranz Mark S et al.

This study directed retinal nerve cell growth onto microelectrodes using patterned surfaces, showing potential to precisely stimulate specific neurons for improved visual prosthetics in degenerative retinal diseases.