Moore Anthony T

Pennesi Mark Edward, Yang Paul, Birch David G, Weng Christina Y, Moore Anthony T, Iannaccone Alessandro et al.

This gene therapy for X-linked retinoschisis was generally safe but showed no measurable clinical benefit in vision, visual fields, or retinal structure, indicating limited efficacy for patients.

Majander Anna, João Catarina, Rider Andrew T, Henning G Bruce, Votruba Marcela, Moore Anthony T et al.

This study found that OPA1-related optic atrophy causes loss in all retinal ganglion cell types, with S-cone related vision worsening significantly with age, potentially serving as a disease progression biomarker.

Godara Pooja, Cooper Robert F, Sergouniotis Panagiotis I, Diederichs Melissa A, Streb Megan R, Genead Mohamed A et al.

This study found inner retinal thinning in GRM6-CSNB, and in Oguchi disease, rods, but not cones, dramatically brighten after dark adaptation, explaining its unique fundus appearance.

Sergouniotis Panagiotis I, Davidson Alice E, Lenassi Eva, Devery Sophie R, Moore Anthony T, Webster Andrew R

Gyrate atrophy showed diverse retinal changes, including macular edema and tubulation, with autofluorescence indicating neurosensory dysfunction. Novel OAT mutations were found, aiding diagnosis and understanding disease progression.

Maubaret Cécilia G, Vaclavik Veronika, Mukhopadhyay Rajarshi, Waseem Naushin H, Churchill Amanda, Holder Graham E et al.

This study found PRPF8 mutations cause adRP with significant variability and incomplete penetrance within families, meaning PRPF8 should be considered in adRP patients with diverse symptoms.

Elgohary Mostafa A, Lim K Sheng, Siriwardena Dilani, Moore Anthony T, Wormald Richard P

Fanconi anemia patients were found to have increased lens thickness, with one developing phacomorphic glaucoma. This novel finding suggests a new ocular complication for FA patients.