Pecen Paula E

Wangyu Stephanie, Jung Jennifer L, Pecen Paula E, Palestine Alan G, Reddy Amit K

A fluocinolone implant effectively treats pediatric uveitis, especially pars planitis, but carries a high risk of ocular hypertension requiring intervention, similar to adult use.

Reddy Amit K, Pecen Paula E, Patnaik Jennifer L, Palestine Alan G

This study found the 0.18-mg fluocinolone acetonide implant effectively treats noninfectious uveitis with low glaucoma rates. It's a viable option, but patient selection and prior steroid use may impact success.

Miller Victoria J, Young Cara E Capitena, SooHoo Jeffrey R, Seibold Leonard K, Kahook Malik Y, Pecen Paula E et al.

KDB goniotomy effectively lowered IOP and reduced medications in uveitis-associated ocular hypertension/glaucoma patients, suggesting it's a safe, less invasive surgical option.

Pattabiraman Padmanabhan P, Pecen Paula E, Rao Ponugoti Vasantha

MRP4 regulates cyclic nucleotides in trabecular meshwork cells. Inhibiting MRP4 increased cAMP/cGMP, relaxed cells, and lowered IOP in rabbits, suggesting a novel target for glaucoma treatment.