Neovascular age-related macular degeneration: intraocular cytokines and growth factors and the influence of therapy with ranibizumab.
Funk Marion, Karl David, Georgopoulos Michael, Benesch Thomas, Sacu Stefan, Polak Kaija et al.
This study found neovascular AMD eyes have high VEGF and low PDGF. Ranibizumab reduced VEGF, correlating with improved vision/anatomy and disease activity, highlighting its anti-VEGF mechanism.