Sase Kana

Kitaoka Yasushi, Sase Kana, Tsukahara Chihiro, Fujita Naoki, Arizono Ibuki, Kogo Jiro et al.

Netarsudil protects optic nerve axons from damage by activating the AMPK-autophagy pathway, suggesting neuroprotective potential beyond intraocular pressure lowering in glaucoma.

Kitaoka Yasushi, Sase Kana, Tsukahara Chihiro, Kojima Kaori, Shiono Akira, Kogo Jiro et al.

Ripasudil, a glaucoma drug, protected optic nerve axons from degeneration in rats by enhancing intra-axonal autophagy. This suggests a novel neuroprotective mechanism beyond pressure lowering.

Kitaoka Yasushi, Kojima Kaori, Munemasa Yasunari, Sase Kana, Takagi Hitoshi

Brimonidine protected rat optic nerve axons from TNF-induced damage and inhibited p62 protein upregulation. This suggests brimonidine's potential for neuroprotection in glaucoma by modulating p62.