Savini Giacomo

Lupardi Enrico, Ferri Monica, Galzignato Alice, Coutinho Catarina P, Laffi Gian Luca, Distefano Andrea et al.

Coutinho Catarina P, Zanchetta Ferdinando, Carbonelli Michele, Battista Marco, Galzignato Alice, La Morgia Chiara et al.

Machine learning identified characteristic visual field patterns in dominant optic atrophy, showing central/ceco-central defects are common. This tool can objectively quantify disease progression and link genotype to functional severity.

Balducci Nicole, Morara Mariachiara, Veronese Chiara, Barboni Piero, Casadei Nicoletta Lelli, Savini Giacomo et al.

OCT-A effectively identified microvascular defects and reduced vessel density in acute ischemic optic neuropathy, offering valuable insights into optic nerve head ischemia.

Savini Giacomo, Hoffer Kenneth J, Schiano Lomoriello Domenico, Ducoli Pietro

Barboni Piero, Savini Giacomo, Carelli Valerio, Balducci Nicole, La Morgia Chiara, Bandello Francesco et al.

Balducci Nicole, Savini Giacomo, Cascavilla Maria Lucia, La Morgia Chiara, Triolo Giacinto, Giglio Rosa et al.

This study found specific, progressive macular nerve fiber and ganglion cell thinning patterns in acute LHON, detectable presymptomatically. This informs future therapies for high-risk individuals and early LHON patients.

Feng Yi-fan, Wang Dan-dan, Zhao Yun-e, Li Jun-hua, Savini Giacomo, Huang Jin-hai

A combined surgical approach effectively treated malignant glaucoma, white cataract, and nanophthalmos in one patient, achieving stable pressure and improved vision without complications.

Ziccardi Lucia, Sadun Federico, De Negri Anna Maria, Barboni Piero, Savini Giacomo, Borrelli Enrico et al.

This study found that unaffected LHON carriers have retinal dysfunction (PERG) without visual pathway conduction issues (VEP), indicating early retinal changes precede overt vision loss.

Huang Jinhai, Savini Giacomo, Wang Qinmei

Savini Giacomo, Barboni Piero, Carbonelli Michele, Sbreglia Alessandra, Deluigi Giulia, Parisi Vincenzo

This study compared ONH measurements from TD-OCT and SD-OCT, finding significant differences in disc area, rim area, and cup-to-disc ratios. These devices are not interchangeable for glaucoma management.

Huang Jinhai, Wang Qinmei, Savini Giacomo

Huang Jinhai, Wang Qinmei, Savini Giacomo

Huang Jinhai, Savini Giacomo, Feng Yifan, Wang Qinmei

Savini Giacomo, Barboni Piero, Parisi Vincenzo, Carbonelli Michele

Axial length impacts OCT measurements of RNFL thickness and optic disc size; longer eyes show thinner RNFL/smaller discs, necessitating magnification correction for accurate glaucoma assessment.

Barboni Piero, Savini Giacomo, Parisi Vincenzo, Carbonelli Michele, La Morgia Chiara, Maresca Alessandra et al.

OCT showed dominant optic atrophy patients have significantly reduced retinal nerve fiber layer thickness, particularly temporal/inferior. This suggests fewer axons at birth, with further age-related loss contributing to visual decline.

Savini Giacomo, Carbonelli Michele, Barboni Piero

SD-OCT offers improved repeatability and diagnostic sensitivity over TD-OCT for glaucoma, with new software enhancing detection. This allows more reliable diagnosis and progression monitoring.

Savini Giacomo, Carbonelli Michele, Barboni Piero

This study compared RNFL thickness measurements between Cirrus-HD OCT and RTVue in healthy eyes, finding RTVue consistently measured thicker, making the results non-interchangeable for clinical comparison.

Barboni Piero, Carbonelli Michele, Savini Giacomo, Foscarini Beatrice, Parisi Vincenzo, Valentino Maria L et al.

OPA1 mutations in dominant optic atrophy patients cause significantly smaller optic nerve heads, a finding that may be mutation-specific and relevant for disease pathogenesis and normal ONH size variation.

Barboni Piero, Carbonelli Michele, Savini Giacomo, Ramos Carolina do V F, Carta Arturo, Berezovsky Adriana et al.

Longitudinal OCT of LHON patients showed initial RNFL thickening (temporal/inferior), followed by widespread thinning. This dynamic evolution suggests a 3-month therapeutic window.

Ramos Carolina do V F, Bellusci Costantino, Savini Giacomo, Carbonelli Michele, Berezovsky Adriana, Tamaki Celina et al.

This study found larger optic discs in LHON carriers and those with visual recovery, suggesting larger disc size may protect against LHON onset and aid recovery.

Savini Giacomo, Espana Edgar M, Acosta Ana Carolina, Carbonelli Michele, Bellusci Costantino, Barboni Piero

This study found adjusting OCT's cup-offset based on cup depth significantly improves agreement with stereophotography for vertical cup-to-disc ratio, enhancing glaucoma diagnostic accuracy.

Bellusci Costantino, Savini Giacomo, Carbonelli Michele, Carelli Valerio, Sadun Alfredo A, Barboni Piero

OCT reveals distinct retinal nerve fiber layer thinning patterns in NAION patients, correlating with specific visual field defects, aiding understanding of disease progression.

Barboni Piero, Savini Giacomo, Valentino Maria Lucia, La Morgia Chiara, Bellusci Costantino, De Negri Anna Maria et al.

This study characterized childhood-onset LHON, finding varied courses and better visual outcomes in slowly progressive cases. These unique features aid LHON pathophysiology understanding and differential diagnosis of childhood vision loss.

Savini Giacomo, Zanini Maurizio, Barboni Piero

Standard OCT effectively visualizes glaucoma filtering blebs, revealing fluid-filled spaces linked to good IOP control and distinct bleb types correlating with surgical methods, aiding post-operative assessment.

Barboni Piero, Savini Giacomo, Valentino Maria Lucia, Montagna Pasquale, Cortelli Pietro, De Negri Anna Maria et al.

OCT showed early LHON causes retinal nerve fiber layer thickening, followed by severe thinning in later stages, with some preservation linked to visual recovery, aiding LHON diagnosis and prognosis.