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The mechanism of action of prostaglandins on uveoscleral outflow.
Schachtschabel U, Lindsey J D, Weinreb R N
Curr Opin OphthalmolApr 200087 citationsReview
Prostaglandins lower eye pressure by activating ciliary muscle receptors, leading to matrix metalloproteinase production. These enzymes remodel ciliary muscle, increasing uveoscleral outflow, clinically relevant for glaucoma treatment.