Shepard A R

Shepard A R, Jacobson N, Fingert J H, Stone E M, Sheffield V C, Clark A F

Dexamethasone indirectly induces MYOC gene expression in human TM cells, suggesting a complex mechanism beyond direct promoter activation. This sheds light on steroid-induced glaucoma pathophysiology.

Clark A F, Steely H T, Dickerson J E, English-Wright S, Stropki K, McCartney M D et al.

Glucocorticoids induce myocilin expression in eye tissues, particularly in eyes developing high pressure, suggesting myocilin's role in steroid-induced and primary open-angle glaucoma.