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Upregulated NOTCH Signaling in the Lens of Patients With Pseudoexfoliation Syndrome Compared With Pseudoexfoliation Glaucoma Suggests Protective Role.
Pradhan Zia S, Dixit Shivani, Krishna Lekshmi, Shetty Reshma, Tejwani Sushma, Rao Harsha L et al.
J GlaucomaMar 20220 citationsObservational Study
Studying NOTCH signaling in pseudoexfoliation, researchers found it upregulated in PXF, but not PXG. This suggests NOTCH activation in the lens may protect against glaucoma development.