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Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork.
Aktas Zeynep, Rao Hongyu, Slauson Sarah R, Gabelt B'Ann T, Larsen Inna V, Sheridan Rachael T C et al.
Invest Ophthalmol Vis SciJan 20180 citationsBasic Science
Proteasome inhibition enhanced lentiviral gene delivery to trabecular meshwork cells and tissues. This could improve gene therapy for glaucoma by boosting therapeutic gene expression.