Su Chien-Chia

Hsu Yung-Ray, Cheng Ming-Shan, Su Chien-Chia, Sun Wen-Hsuan, Wang Jia-Kang

This study found that CMV anterior uveitis eyes have significantly higher background IOP volatility and faster retinal nerve fiber layer loss, suggesting chronic, aggressive glaucoma development.

Hsu Yung-Ray, Gao Chia-Mao, Chin Wei-Yao, Miaw Shi-Chuen, Wang I-Jong, Su Chien-Chia

This study found CMV anterior uveitis patients have elevated CMV-specific T-cell responses (IFN-γ, TNF-α) correlating with longer disease duration and worse glaucoma, suggesting these immune responses shape clinical outcomes.

Hsia Yun, Chang Fang-Ying, Su Chien-Chia, Wang Tsing-Hong, Huang Jehn-Yu

Hsia Yun, Chang Hsiao-Lien, Wang Tsing-Hong, Huang Jehn-Yu, Su Chien-Chia

This study found OCTA artifacts, especially defocus, are common and increase with glaucoma severity, impacting scan variability. Clinically, careful artifact assessment is crucial for accurate interpretation.

Hsia Yun, Wang Chi, Su Chien-Chia, Huang Jehn-Yu, Wang Tsing-Hong, Tu Yu-Kang

This study found PGFA-based combinations (especially with CAI) and non-PGFA triple combinations most effective for IOP reduction. Crucially, it identified drug antagonisms (PGFA+BAB/ROCKI) and synergies (PGFA+CAI).

Su Chien-Chia, Desikan Vaibhav, Betsch Kevin, Shim Myoung Sup, Keller Kate E, Liton Paloma B

Studying TM cells, researchers found mechanical stress increases tubulin acetylation, stabilizing microtubules. This process, elevated in glaucoma, can lower IOP, suggesting tubulin acetylation as a glaucoma therapeutic target.

Lai I-Wen, Wang Tsing-Hong, Huang Jehn-Yu, Su Chien-Chia

This study found that decreased vessel density, particularly radial peripapillary capillary and macular, is linked to early contrast sensitivity impairment in glaucoma, serving as an indicator for early disease.

Su Chien-Chia, Wang Tsing-Hong, Huang Jehn-Yu, Liao Kuo-Meng, Tsai Li-Ting

This study found glaucoma patients' stair descent time correlated best with visual function, especially contrast sensitivity and inferior visual field. Clinically, impaired vision requires advising patients on stair safety and low-vision referral.

Su Chien-Chia, Lee Yi-Chieh, Lee Peter Richmond Candano

Su Chien-Chia, Gao Chia-Mao, Peng Fu-Ti, Jou Tzuu-Shuh, Wang I-Jong

A rat model of CMV eye infection showed glucocorticoids hinder viral clearance, while ganciclovir aids immune response, impacting treatment strategies for human CMV anterior segment disease.

Hsia Yun, Wang Tsing-Hong, Huang Jehn-Yu, Su Chien-Chia

In advanced glaucoma, central visual field defects and macular vessel density loss are linked to disability glare, significantly impacting patients' quality of life.

Hsia Yun, Wang Tsing-Hong, Huang Jehn-Yu, Su Chien-Chia

This study found macular vessel density, especially deep layers, strongly correlates with visual acuity in advanced and severe glaucoma, suggesting it's a promising clinical biomarker.

Chen Ying-Yi, Wang Tsing-Hong, Huang Jehn-Yu, Su Chien-Chia

This study found NTG eyes are more compliant than healthy eyes. Crucially, longer axial length is a major risk factor for unilateral NTG, suggesting optic nerve strain's role in disease development.

Hsia Yun, Lai Tso-Ting, Su Chien-Chia, Wang Tsing-Hong, Huang Jehn-Yu

This study on primary congenital glaucoma found that aggressive IOP control is crucial to prevent structural and functional decline, with fellow eyes not at risk.

Hsia Yun, Su Chien-Chia, Wang Tsing-Hong, Huang Jehn-Yu

Acute angle-closure eyes showed significantly higher posture-related IOP increases, especially in lateral decubitus, linked to narrower angles. This highlights the importance of positional IOP monitoring in these patients.

Su Chien-Chia, Lee Yi-Chieh, Lee Peter Richmond Candano

BAK-preserved latanoprost worsened ocular surface health by decreasing tear secretion. Artificial tears may mitigate this in vulnerable glaucoma patients, highlighting the need for early intervention.

Hsia Yun, Su Chien-Chia, Wang Tsing-Hong, Huang Jehn-Yu

This study found disc hemorrhages in supero/inferotemporal regions predict faster glaucoma progression (RNFL thinning, visual field loss) than those elsewhere, highlighting high-risk locations.

Hsia Yun, Su Chien-Chia, Wang Tsing-Hong, Yang Chung-May, Huang Jehn-Yu

Long-term study of retinal nerve fiber layer cleavages in glaucoma patients/suspects found no detectable structural or functional progression, suggesting they may not indicate worsening glaucoma.

Su Chien-Chia, Chen Judy Yi-Chu, Wang Tsing-Hong, Huang Jehn-Yu, Yang Chung-May, Wang I-Jong

This study found that in glaucoma patients, higher comorbidity burden, particularly with systemic beta-blockers and calcium channel blockers, significantly increases depression risk, not topical glaucoma medications.