Ticho U

Blumenthal E Z, Muszkat M, Pe'er J, Ticho U

A rare thymic tumor causing Cushing syndrome led to severe glaucoma, which resolved after tumor removal, highlighting systemic causes of ocular hypertension.

Chowers I, Ticho U

This study found Mitomycin-C in combined or sequential trabeculectomy/corneal transplant effectively controlled IOP (91%) and maintained graft clarity (82%) for coexisting glaucoma and corneal disease, with minimal MMC-related complications.

Lusky M, Ticho U, Glovinsky J, Weinberger D, Nesher R, Yassur Y et al.

This study compared two latanoprost regimens for elevated IOP, finding 50 µg/ml once daily was significantly more effective than 15 µg/ml twice daily, guiding optimal glaucoma treatment.

Ticho U, Ophir A

This study found glaucoma filtering surgery with 5-FU, while effective, carries various late bleb-related complications like endophthalmitis, leaks, and hypotony, impacting long-term safety.

Backon J, Matamoros N, Ramirez M, Sanchez R M, Ferrer J, Brown A et al.

Forced right nostril breathing significantly lowered intraocular pressure (IOP) in most glaucoma patients, suggesting a non-pharmacological method to reduce IOP, though some patients experienced an increase.

Ophir A, Ticho U

Repeat filtering surgery with 5-FU was studied in five patients with failed prior surgery. It successfully lowered IOP in all cases, suggesting it's a favorable option for refractory glaucoma.

Backon J, Matamoros N, Ticho U

Forced unilateral nostril breathing significantly altered IOP: left nostril breathing (right brain activation) increased IOP by 4.5%, while right nostril breathing (left brain activation) decreased IOP by 25%. This suggests a novel brain-autonomic pathway influencing IOP.

Frucht J, Bishara S, Ticho U

Laser trabeculoplasty can cause early, significant IOP spikes in 42% of patients, often within the first hour. Monitoring for at least 4 hours post-procedure is crucial to prevent silent hypertensive risk.

Ticho U, Lahav M, Berkowitz S, Yoffe P

Steroid-induced high eye pressure in rabbits showed abnormal accumulation of acid mucopolysaccharides in the chamber angle, suggesting a mechanism for this glaucoma type.

Mazor Z, Ticho U, Rehany U, Rose L

Piloplex caused less visual disturbance than pilocarpine, allowing twice-daily dosing for glaucoma patients, reducing daily visual side effects compared to four-times-daily pilocarpine.

Ticho U, Blementhal M, Zonis S, Gal A, Blank I, Mazor Z W

Piloplex, a new long-acting pilocarpine, lowered IOP more effectively twice daily than standard pilocarpine four times daily, with fewer side effects. This offers improved glaucoma treatment adherence and tolerance.

Ticho U, Cadet J C, Mahler J, Sekeles E, Bruchim A

Argon laser trabeculotomies in primates showed initial tissue damage and improved outflow, but healing caused complete closure and lost efficacy within weeks, limiting long-term benefit.

Ticho U, Ivry M

Argon laser treatment reopened 5 of 11 occluded glaucoma filtering blebs, normalizing IOP, particularly in cases with incomplete scarring. This offers a non-surgical option for failing blebs.

BenEzra D, Ticho U, Sachs U

This study found open-angle glaucoma patients' lymphocytes were not more sensitive to glucocorticoids than controls, suggesting this isn't a specific glaucoma biomarker.