Torrejon Karen Y

Brown Suzette Farber-Katz, Nguyen Hien, Mzyk Philip, De Ieso Michael L, Unser Andrea M, Brown Ian et al.

This study found ANGPTL7 increases eye pressure by raising outflow resistance. Blocking ANGPTL7 lowered eye pressure in models, suggesting it's a promising target for new glaucoma therapies.

Li Guorong, Torrejon Karen Y, Unser Andrea M, Ahmed Feryan, Navarro Iris D, Baumgartner Rudolf A et al.

Trabodenoson lowers IOP in mice by increasing outflow facility via TM extracellular matrix remodeling, suggesting a novel glaucoma treatment mechanism.