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Timing of corticosteroid therapy is critical to prevent retinal ganglion cell loss in experimental optic neuritis.
Dutt Mahasweta, Tabuena Philomela, Ventura Elvira, Rostami Abdolmohamad, Shindler Kenneth S
Invest Ophthalmol Vis SciMar 201034 citationsBasic Science
Studying experimental optic neuritis, early corticosteroid treatment before inflammation onset prevented retinal ganglion cell loss, but later treatment was less effective. This suggests chronic immunomodulation may be crucial.