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Vohra Rupali

4 articles in GJC

4 articles in GJC

1.

Semaglutide Protects Retinal Ganglion Cells Against Rotenone-Induced Degeneration via Improved Glucose Metabolism.

Mouhammad Zaynab A, Tribble James R, Nicol Alan, Andreopoulou Evgenia, García-Bermúdez Mariana Y, Aldana Blanca I et al.

Invest Ophthalmol Vis SciFeb 20260 citationsBasic Science

Semaglutide protected retinal ganglion cells from degeneration in a glaucoma model by enhancing retinal glucose metabolism, suggesting a potential neuroprotective strategy for glaucoma via metabolic flexibility.

2.

When Is a Control Not a Control? Reactive Microglia Occur Throughout the Control Contralateral Pathway of Retinal Ganglion Cell Projections in Experimental Glaucoma.

Tribble James R, Kokkali Eirini, Otmani Amin, Plastino Flavia, Lardner Emma, Vohra Rupali et al.

Transl Vis Sci TechnolJan 202138 citationsBasic Science

Unilateral glaucoma models showed significant microglial activation in the contralateral "control" eye and visual pathways. This suggests caution when using the contralateral eye as a control in glaucoma research.

3.

Potential metabolic markers in glaucoma and their regulation in response to hypoxia.

Vohra Rupali, Dalgaard Line Marie, Vibaek Jeppe, Langbøl Mia Aggergaard, Bergersen Linda Hildegaard, Olsen Niels Vidiendal et al.

Acta OphthalmolJan 20190 citationsObservational Study

This study found NTG patients had lower baseline serum lactate and amino acids, with altered hypoxic responses. This suggests systemic metabolic differences linked to NTG, potentially aiding diagnosis and understanding.

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