Vujosevic Stela

Vujosevic Stela, Parra M Margarita, Hartnett M Elizabeth, O'Toole Louise, Nuzzi Alessia, Limoli Celeste et al.

Optical Coherence Tomography (OCT) non-invasively detects retinal changes (e.g., nerve fiber layer thinning, hyper-reflective spots) in systemic neuroinflammatory/neurodegenerative diseases in adults and children, serving as a valuable CNS biomarker.

Midena Edoardo, Bini Silvia, Martini Ferdinando, Enrica Convento, Pilotto Elisabetta, Micera Alessandra et al.

Subthreshold micropulse laser for diabetic macular edema improved vision, reduced macular thickness, and decreased Müller cell dysfunction markers (GFAP, Kir 4.1) and VEGF, suggesting it restores Müller cell function.

Vujosevic Stela, Muraca Andrea, Alkabes Micol, Villani Edoardo, Cavarzeran Fabiano, Rossetti Luca et al.

This study found early neural and microvascular changes in both Type 1 and Type 2 diabetes before retinopathy, with perifoveal capillary loss correlating with inner retinal thinning. This aids preclinical diabetic retinopathy characterization.

Vujosevic Stela, Muraca Andrea, Gatti Valentina, Masoero Luca, Brambilla Marco, Cannillo Barbara et al.

This study found early peripapillary microvascular changes and nerve thinning in diabetics without retinopathy, suggesting early nerve and vessel damage. This could aid earlier detection.

Vujosevic Stela, Simó Rafael

This review found local eye inflammation, driven by retinal cells, is key in diabetic retinopathy. Biomarkers and imaging can monitor disease and guide personalized treatment.

Vujosevic Stela, Micera Alessandra, Bini Silvia, Berton Marianna, Esposito Graziana, Midena Edoardo

This study found Müller cell activation biomarkers (GFAP, AQP1, AQP4) are significantly elevated in diabetic eyes, even before visible retinopathy, indicating early retinal damage and potential for early intervention.

Vujosevic Stela, Martini Ferdinando, Cavarzeran Fabiano, Pilotto Elisabetta, Midena Edoardo

This study found choroidal thickness (CT) progressively decreases with increasing diabetic retinopathy severity. This suggests CT reduction is linked to DR progression, highlighting the choroid's potential role in DR pathophysiology.