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Genetic dissection of the Gpnmb network in the eye.
Lu Hong, Wang Xusheng, Pullen Matthew, Guan Huaijin, Chen Hui, Sahu Shwetapadma et al.
Invest Ophthalmol Vis SciJun 201121 citationsBasic Science
Studying Gpnmb in mouse eyes, researchers found a mutation drastically alters its gene network, shifting from melanin/cell migration to stress/post-translational modification, potentially explaining pigmentary glaucoma pathology.