1.
Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis.
Fisher Jennifer B, Jacobs Dina A, Markowitz Clyde E, Galetta Steven L, Volpe Nicholas J, Nano-Schiavi M Ligia et al.
OphthalmologyFeb 2006492 citationsCross-Sectional Study
This study found MS patients have thinner RNFL, even without optic neuritis, which correlates with worse low-contrast vision. This supports RNFL and low-contrast acuity as MS trial biomarkers.