Xing Yiqiao

Zhu Feiyan, Feng Jiazhen, Pan Yiji, Ouyang Lingyi, He Tao, Xing Yiqiao

Mettl3-mediated m6A modification protects against retinal ganglion cell loss and dysfunction in retinal ischemia-reperfusion injury by inhibiting FoxO1-mediated autophagy, offering a potential therapeutic target for glaucoma.

Ouyang Lingyi, He Tao, Xing Yiqiao

Studying optic nerve crush, researchers found that Park7 downregulation worsened retinal ganglion cell injury and visual function via the Nrf2 pathway, suggesting Park7 is a neuroprotective target for optic neuropathy.

Xie Feijia, Li Zongyuan, Yang Ning, Yang Jiayi, Hua Dihao, Luo Jinyuan et al.

Inhibiting HspB8 in mouse optic nerve injury protected retinal ganglion cells and function by suppressing autophagy, suggesting a potential therapeutic target for glaucoma.

Zhang Ningzhi, Cao Wenye, He Xuejun, Xing Yiqiao, Yang Ning

Cold methanol effectively preserves mouse retinas for long-term storage (up to 12 months) without compromising immunostaining results for vasculature, hypoxia, or RGCs, aiding glaucoma and retinal research.

Zhang Ningzhi, He Xuejun, Xing Yiqiao, Yang Ning

This review highlights that different retinal ganglion cell (RGC) subtypes show varying susceptibility to neurodegenerative diseases, which is crucial for developing targeted therapies to prevent vision loss.

Luo Jinyuan, He Tao, Yang Jiayi, Yang Ning, Li Zongyuan, Xing Yiqiao

This study found SIRT1 activation by resveratrol protected retinal ganglion cells from damage in an acute glaucoma model, suggesting SIRT1 activators could be a therapeutic strategy.

Mei Haifeng, Xing Yiqiao, Yang Anhuai, Wang Jing, Xu Ya, Heiligenhaus Arnd

This study found intraoperative suprachoroidal hemorrhage during vitrectomy in traumatized eyes is linked to hypotony or scleral depression. Clinically, avoid abrupt hypotony and pars plana pressure in these high-risk cases.