Yang Chang-Hao

Cheng Chien-Chien, Lin Chien-Yu, Ko Ting-Chieh, Huang Yu-Shu, Huang Chu-Hsuan, Yang Chang-Hao et al.

Taiwanese Alström syndrome patients showed variable ocular and systemic features, with a common Asian genotype linked to severe disease, while a novel LINE-1 insertion correlated with milder phenotypes, aiding diagnosis.

Yeh Po-Ting, Lin Feng-An, Lin Chang-Pin, Yang Chung-May, Chen Muh-Shy, Yang Chang-Hao

This study found lymphotactin and its receptor XCR are upregulated in inflamed eye tissue in rat autoimmune uveitis, attracting immune cells. Inhibiting this pathway could reduce inflammation, offering a potential therapeutic target.

Yang Chang-Hao, Fang I-Mo, Lin Chang-Pin, Yang Chung-May, Chen Muh-Shy

This study found that an NF-kappaB inhibitor reduced inflammation and chemokine expression in experimental autoimmune uveitis, suggesting NF-kappaB blocking is a potential treatment for acute anterior uveitis.