Zangwill L M

Bowd C, Tafreshi A, Zangwill L M, Medeiros F A, Sample P A, Weinreb R N

This study found PERG amplitude significantly correlates with macular GCC and RNFL thickness in glaucoma, suggesting PERG reflects inner retinal ganglion cell health, aiding early detection and monitoring.

Balasubramanian M, Bowd C, Weinreb R N, Zangwill L M

This study found HRT-I and HRT-II aren't interchangeable for glaucoma change detection without parabolic error correction. Applying this correction allows HRT-I data to be reliably included in longitudinal HRT-II series.

Vizzeri G, Weinreb R N, Gonzalez-Garcia A O, Bowd C, Medeiros F A, Sample P A et al.

This study found SD-OCT is repeatable, but TD-OCT measures thicker RNFL. While agreement is good, these instruments' measurements are not interchangeable for glaucoma management.

Sanchez-Galeana C, Bowd C, Blumenthal E Z, Gokhale P A, Zangwill L M, Weinreb R N

HRT, GDx, and OCT summary data can differentiate early glaucoma from normal eyes, but their moderate sensitivity/specificity means they're insufficient as standalone screening tools.

Tannenbaum D P, Zangwill L M, Bowd C, Sample P A, Weinreb R N

This study found significant overlap in nerve fiber layer measurements between large cup-to-disk ratio eyes with and without visual field defects, limiting scanning laser polarimetry's early glaucoma detection utility in these patients.

Zangwill L M, Weinreb R N

Bowd C, Zangwill L M, Berry C C, Blumenthal E Z, Vasile C, Sanchez-Galeana C et al.

This study compared early glaucoma detection methods, finding OCT and FDT perimetry generally outperformed SLP and SWAP in identifying early disease, suggesting their superior clinical utility.

Blumenthal E Z, Williams J M, Weinreb R N, Girkin C A, Berry C C, Zangwill L M

This study found OCT RNFL measurements are reproducible in normal and glaucoma eyes, with most variability between patients, not due to technicians or visits. This supports OCT's reliability for glaucoma monitoring.

Bowd C, Weinreb R N, Lee B, Emdadi A, Zangwill L M

IOP reduction with latanoprost showed no overall optic disc topographic changes, but significant decreases (≥7mmHg) improved cup/rim parameters. This means IOP should be considered when monitoring glaucoma progression.

Zangwill L M, Williams J, Berry C C, Knauer S, Weinreb R N

This study found OCT retinal nerve fiber layer thickness strongly correlates with photographic and visual field damage in glaucoma, showing promise for quantitative diagnosis and monitoring.

Zangwill L M, Berry C C, Weinreb R N

Pupil dilation generally doesn't alter optic disc measurements if initial image quality is good, but poor image quality warrants caution.

Zangwill L M, van Horn S, de Souza Lima M, Sample P A, Weinreb R N

This study found ocular hypertensive eyes have optic nerve topography measurements intermediate between normal and glaucoma eyes, aiding in risk assessment and differentiation.