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PRMT5 Regulates Senescence in Retinal Ganglion Cells by Targeting the Wnt/β-Catenin Signaling Cascade.
Zhang Yumeng, Huang Hanwen, Zhong Huimin, Zhang Yang, He Siqi, Guo Yanzhi et al.
Invest Ophthalmol Vis SciJun 20251 citationsBasic Science
This study found PRMT5 downregulation in glaucoma leads to RGC senescence via the Wnt/β-catenin pathway, suggesting this pathway is a promising therapeutic target to prevent RGC degeneration.