Addis Victoria

The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men.

The V83I polymorphism was associated strongly with POAG in AA men and disrupts Aβ-binding to CO1. This region also interacts with a neuroprotective protein, UBQLN1.

Prevalence and Factors Associated with Optic Disc Tilt in the Primary Open-Angle African American Glaucoma Genetics Study.

There are substantial numbers of tilted optic discs in glaucoma patients with African ancestry. They occur more frequently in female subjects and younger subjects and are associated with several ocular features but not with myopia.

Evaluation of the Cirrus High-Definition OCT Normative Database Probability Codes in a Black American Population.

Results further establish the presence of structural differences in the RNFL of Black American patients.

Low Body Mass Index Poses Greater Risk of Primary Open-Angle Glaucoma in African Ancestry Individuals.

In this African ancestry cohort, low BMI was associated with increased POAG risk.

Outcomes of Trabeculectomy and Predictors of Success in Patients of African Ancestry With Primary Open Angle Glaucoma.

This study underscores the low rates of trabeculectomy success and high rates of complications in an African ancestry population with POAG.

Predictors of Glaucoma Conversion in an African Ancestry Cohort: A Longitudinal Study.

In glaucoma suspects of African ancestry, higher risk of POAG conversion is independently associated with higher IOP, absence of hypertension, and presence of myopia.

Risk factors associated with beta-peripapillary atrophy in individuals of African ancestry with primary open-angle glaucoma.

Beta-PPA is strongly associated with older age and high CDR among individuals with POAG. These regions are vulnerable to RNFL loss.

Self-identified Black Race as a Risk Factor for Intraocular Pressure Elevation and Iritis Following Prophylactic Laser Peripheral Iridotomy.

The incidence of immediate IOP elevation and iritis following prophylactic LPI was higher in Black patients independent of laser type and energy.

Trabeculectomy in Patients With Glaucoma Over 80 Years of Age: Relatively Short-term Outcomes.

The surgical outcomes of trabeculectomy in patients older than 80 years were found to be similar to those of younger controls.