Alward Wallace L M

Optical Coherence Tomography Analysis Based Prediction of Humphrey 24-2 Visual Field Thresholds in Patients With Glaucoma.

The proposed RGC-AC optimized predictive algorithm based on 9-field OCT image analysis and the RGC-AC concept is superior to previous methods and its performance is close to the reproducibility of HVF 24-2.

Myocilin Mutations in Patients With Normal-Tension Glaucoma.

In cohorts 1 and 2, the p.Gln368Ter mutation in MYOC was found in patients with IOPs that were 21 mm Hg or lower (NTG), although at a frequency that is lower than previously detected in patients with higher IOP.

The Heritability of Pigment Dispersion Syndrome and Pigmentary Glaucoma.

Most of the cases of PDS in our study were sporadic, and the risk to first-degree relatives is lower than previously reported.

Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye.

This is the first histopathological analysis of an eye from a glaucoma patient with amutation.

GJA3 Genetic Variation and Autosomal Dominant Congenital Cataracts and Glaucoma Following Cataract Surgery.

The GJA3 genetic variant, p.Asp67Tyr, was identified in a 4-generation congenital cataract pedigree from Iowa.

Gonioscopy-Assisted Transluminal Trabeculotomy for Myocilin Juvenile Glaucoma.

Posterior Embryotoxon Revisited: An Immunohistologic Study.

In contrast to the widely accepted definition of PE as a prominent, anteriorly displaced Schwalbe line, histologic evidence suggests that it is a direct extension of the corneal stroma with variable locations that may displace…

Accurate Identification of the Trabecular Meshwork under Gonioscopic View in Real Time Using Deep Learning.

Our CNN model can identify the TM in gonioscopy videos in real time with remarkable accuracy, allowing it to be used in connection with a video camera intraoperatively.

Genomic Organization of TBK1 Copy Number Variations in Glaucoma Patients.

No specific mutation hotspots for TBK1 CNVs were detected, however, interspersed repetitive sequences (ie, Alu elements) were identified at the borders of TBK1 CNVs, which suggest that mismatch of these elements during meiosis may be…

Gonioscopy-Assisted Transluminal Trabeculotomy for Myocilin-Associated Juvenile Open-Angle Glaucoma: A Case Series of 8 Eyes Over 2.2 to 4.1 Years.

In MYOC-associated JOAG, the pathology is concentrated at the trabecular meshwork (TM), lending itself well to angle-based surgeries, especially GATT.

Aqueous Misdirection After Trabeculectomy in a Down Syndrome Patient With Angle-closure Glaucoma.

Patients with Down syndrome often have small, hyperopic eyes with narrow iridocorneal angles and may be at increased risk for aqueous misdirection associated with surgical procedures.

Ptosis Masquerading as Progression of Severe Glaucoma.

Progressive optic disc cupping over 20 years in a patient with-associated glaucoma.

Thrombospondin Mutations and Patients With Primary Congenital Glaucoma in a United States Population.

However, none of these variants were judged to be disease-causing mutations based on: 1) prevalence in cases and controls from Iowa, 2) prevalence in the public database gnomAD, 3) mutation analysis algorithms, and 4) THBS1 DNA sequence conservation.

The Invisible Paper that Shook Ophthalmology.

In-the-Bag Intraocular Lens Subluxation in a Patient with Exfoliation Glaucoma.

Traumatic Pigment Dispersion Syndrome.

Upper Eyelid Splitting to Facilitate the Insertion of Glaucoma Drainage Devices.

A variety of congenital or acquired conditions result in narrowing of the palpebral fissure or restriction of extraocular motility.

The Utility of Diaton Tonometer Measurements in Patients With Ocular Hypertension, Glaucoma, and Glaucoma Tube Shunts: A Preliminary Study for its Potential Use in Keratoprosthesis Patients.

Diaton tonometry has a large margin of error compared with GAT in patients with ocular hypertension, glaucoma, and glaucoma tube shunts.

Boston type 1 keratoprosthesis for primary congenital glaucoma.

The Boston KPro-1 has an excellent prognosis for retention in eyes with congenital glaucoma.

Iridocorneal Endothelial Syndrome in a 14-Year-Old Male.

The iridocorneal endothelial syndrome is a rare cause of unilateral glaucoma that is almost never seen in children.

Boston Type 1 Keratoprosthesis for Iridocorneal Endothelial Syndromes.

The Boston KPro-1 may offer a better prognosis than repeat traditional keratoplasty in reestablishing corneal clarity in eyes with iridocorneal endothelial syndromes.

Movement of Retinal Vessels to Optic Nerve Head with Intraocular Pressure Elevation in a Child.