Aspberg Johan

Screening for Open-Angle Glaucoma and Its Effect on Blindness.

The results suggest that population screening may reduce bilateral low vision and blindness caused by glaucoma by approximately 50%.

Initial intraocular pressure reduction by mono- versus multi-therapy in patients with open-angle glaucoma: results from the Glaucoma Intensive Treatment Study.

Intensive treatment led to considerably greater IOP reduction than mono-therapy.

The Glaucoma Intensive Treatment Study (GITS), a randomized clinical trial: design, methodology and baseline data.

Glaucoma Intensive Treatment Study is a clinical trial in which two groups of patients randomized to different initial intensities of IOP-reducing treatment are being compared with regard to rate of visual field progression and prediction…

The glaucoma intensive treatment study: interim results from an ongoing longitudinal randomized clinical trial.

The rate of disease progression was significantly slower in the multi-treated patients than in the mono-treated patients. Further follow-up will show whether this difference is sustained over time.

Intraocular Pressure Lowering Effect of Latanoprost as First-line Treatment for Glaucoma.

To the best of our knowledge, this paper is the first to report the IOP-reducing effect of latanoprost treatment at all untreated IOP levels in newly detected glaucoma patients.

Laser trabeculoplasty in newly diagnosed multi-treated glaucoma patients.

Success of LTP was highly dependent on the IOP level prior to LTP treatment.

Long-term follow-up of laser trabeculoplasty in multi-treated glaucoma patients.

LTP performed in multi-treated patients may provide a useful IOP reduction that is maintained over several years.

Estimating the Length of the Preclinical Detectable Phase for Open-Angle Glaucoma.

The mean PCDP was similar for both methods of analysis, approximately 10 years. A mean PCDP of 10 years found in the current study allows for screening with reasonably long intervals, eg, 5 years.

Threat to fixation and vision-related quality of life in early open-angle glaucoma - results from the Glaucoma Intensive Treatment Study.

The presence of TTF did not influence VRQoL, as measured by the NEI-VFQ-25, in this relatively large group of patients with mainly early glaucoma.

The Glaucoma Intensive Treatment Study (GITS): A Randomized Controlled Trial Comparing Intensive and Standard Treatment on 5 Years Visual Field Development.

In the overall analysis, the visual field outcomes were not overwhelmingly better in the multi-treatment group, but post hoc analysis showed definite benefit in patients with higher untreated IOP.

Impact of mono- or multitherapy on ocular surface health and quality of life after 5 years of follow-up in the Glaucoma Intensive Treatment Study (GITS).

We found no differences in objective or subjective impact on ocular surface between the two randomization arms.

Corrigendum to "The Glaucoma Intensive Treatment Study (GITS): A Randomized Controlled Trial Comparing Intensive and Standard Treatment on 5 Years Visual Field Development" [Am J Ophthalmol 2024;266:274-288].