Aziz Kanza

Risk Factors for Repeat Keratoplasty after Endothelial Keratoplasty in the Medicare Population.

Blacks or Asians, comorbid glaucoma, concurrent or prior glaucoma surgery, and lower volumes of surgery are associated with increased risk of repeated keratoplasty. Racial disparities identified in this study warrant further investigation.

Postoperative Complications in Medicare Beneficiaries Following Endothelial Keratoplasty Surgery.

The incidence of major postoperative complications including endophthalmitis, retinal detachment, and choroidal hemorrhage following EK procedures is low.

Lessons Learned From 2 Large Community-based Glaucoma Screening Studies.

This editorial highlights lessons learned from 2 large prospective trials: the Philadelphia Telemedicine Glaucoma Detection and Follow-up Study and the Screening To Prevent Glaucoma Study.

Treatment Patterns of Childhood Glaucoma in the United States: Analysis of IRISRegistry (Intelligent Research in Sight).

We found that 1 in 6 childhood glaucoma eyes underwent glaucoma-related procedures, and nearly all received antiglaucoma medications.

Primary Open-Angle Glaucoma Polygenic Risk Score and Risk of Disease Onset: A Post Hoc Analysis of a Randomized Clinical Trial.

These findings support considering use of a POAG PRS threshold to identify individuals at low risk of disease onset, with those below the PRS threshold more likely to have lower conversion rates over 20 years.

Long-Term Outcomes from an Intraoperative Bleb Needling Procedure Augmented with Continuous Infusion.

Reductions in IOP were maintained in most patients over the long term using a modified bleb needling technique, despite an average time from trabeculectomy of over 4 years.

Geographic Distribution of Access to Glaucoma Surgery: An IRIS® Registry (Intelligent Research in Sight) Analysis.

Patients are more likely to receive most types of glaucoma surgeries in urban practice locations.

ChatGPT-Assisted Glaucoma Diagnosis: A Health-Equitable Multi-Ancestry Analysis Using Visual Field and Optical Coherence Tomography Data.

ChatGPT o1 Pro diagnosed glaucoma similarly to specialists using only VF and OCT data. The model performance was similar across ancestral groups and genetic predispositions to glaucoma.

Glaucoma Polygenic Risk Scores Demonstrate Heterogeneous Performance across 2 Large Multiethnic Cohorts.

Our results demonstrate that while PRSs predict glaucoma risk at the cohort level, their instability at the individual level limits stand-alone clinical application.