Sally L. Baxter

Machine Learning-Based Predictive Modeling of Surgical Intervention in Glaucoma Using Systemic Data From Electronic Health Records.

Existing systemic data in the EHR has some predictive value in identifying POAG patients at risk of progression to surgical intervention, even in the absence of eye-specific data.

Racial and Ethnic Disparities in Cost-Related Barriers to Medication Adherence Among Patients With Glaucoma Enrolled in the National Institutes of Health All of Us Research Program.

In this study, there was significantly higher odds of self-reported difficulty affording medications among non-Hispanic African American and Hispanic individuals compared with non-Hispanic White individuals.

Predictive Analytics for Glaucoma Using Data From the All of Us Research Program.

Models trained with national AoU data achieved superior performance compared with using single-center data.

Impact of Smoking on Visual Field Progression in a Long-term Clinical Follow-up.

Heavy smokers are more likely to sustain VF loss in eyes with glaucoma.

Associations between Socioeconomic Factors and Visit Adherence among Patients with Glaucoma in the All of Us Research Program.

Lower income and education levels were significantly associated with lower odds of seeing an eye doctor in the past year among all patients with glaucoma in All of Us.

Is Diabetes Mellitus a Blessing in Disguise for Primary Open-angle Glaucoma?

This article discusses progress in understanding the complex relationship between these 2 entities and recent shifts in perspective that challenge the traditional dogma regarding diabetes mellitus and primary open-angle glaucoma.

Racial, Ethnic, and Socioeconomic Disparities in Glaucoma Onset and Severity in a Diverse Nationwide Cohort in the United States.

Black, Hispanic/Latino, and other minority participants are diagnosed with glaucoma at younger ages, and Blacks are more likely to be diagnosed with moderate-to-severe glaucoma.

Social determinants of health and health disparities in glaucoma: A review.

These disparities highlight potential targets for interventions to combat these disparities and improve overall patient outcomes.

Usability and Clinician Acceptance of a Deep Learning-Based Clinical Decision Support Tool for Predicting Glaucomatous Visual Field Progression.

A CDS tool can be designed to present AI model outputs in a useful, trustworthy manner that clinicians are generally willing to integrate into their clinical decision-making.

Novel Technologies in Artificial Intelligence and Telemedicine for Glaucoma Screening.

Leveraging novel technologies and advances in telemedicine and AI-based approaches to glaucoma detection show promise for improving our ability to detect moderate and advanced glaucoma in primary care settings and target higher individuals at high…

Smoking Cessation May Reduce Risk of Visual Field Progression in Heavy Smokers.

After ≥25 years of smoking cessation, the risk of VF progression in former heavy smokers becomes similar to never smokers. Long-term smoking cessation may be associated with lower VF progression in glaucoma patients.

Relationship Between Glaucoma and Chronic Stress Quantified by Allostatic Load Score in the All of Us Research Program.

AoU participants with glaucoma had greater AL 6.4 years before diagnosis, and the AL score partially mediated racial or ethnic differences in glaucoma risk.

Federated Learning in Glaucoma: A Comprehensive Review and Future Perspectives.

Federated Learning presents a promising strategy to overcome current obstacles in developing AI models for glaucoma screening.

Breaking Barriers in Behavioral Change: The Potential of Artificial Intelligence-Driven Motivational Interviewing.

Domain-specific training may be needed to ensure the accuracy and completeness of information provided in subspecialty areas such as glaucoma.

Gender Disparities in Depression, Stress, and Social Support Among Glaucoma Patients.

Women with glaucoma were more likely to experience depression and stress and were less likely to have social support on some measures than men.

Social and Health Care Utilization Factors Associated With Ophthalmic Visit Nonadherence in Glaucoma: An All of Us Study.

This study builds on prior literature by identifying potentially modifiable factors associated with visit nonadherence and underutilization of eyecare in glaucoma.

Healthcare Access and Utilization Among Glaucoma Patients in a Nationwide Cohort.

Although glaucoma patients aged 65 years and over fared worse on several measures of socioeconomic status, no significant difference was found in measures of healthcare access and utilization.

Long-Term Systemic Use of Calcium Channel Blockers and Incidence of Primary Open-Angle Glaucoma.

Use of dihydropyridine CCBs was associated with a significantly higher risk of developing POAG, both before and while adjusting for demographic factors and comorbid medical conditions.

Association Between Glucagon-Like Peptide-1 Receptor Agonists Exposure and Intraocular Pressure Change: GLP-1 Receptor Agonists and Intraocular Pressure Change.

Although GLP-1R agonists were significantly associated with a decrease in IOP in the paired analysis, they were not associated with ΔIOP in multivariable GEE. Moreover, the difference in ΔIOP between the two groups was small.

Gap Analysis of Glaucoma Examination Concept Representations within Standard Systemized Nomenclature of Medicine - Clinical Terms.

There are existing gaps in the standardized representation of findings related to tonometry and gonioscopy within SNOMED-CT.

Performance of General-Purpose Vision Language Models and Ophthalmology Foundation Models in Glaucoma Detection and Function Prediction.

Fine-tuned VLMs demonstrated high performance in glaucoma detection and VF MD prediction, matching or exceeding specialized foundation models and traditional convolutional neural network (CNN)-based methods.

Gap Analysis of Standard Automated Perimetry Concept Representation in Medical Terminologies.

There is a lack of representation of some SAP data elements in standardized medical terminologies, hampering interoperability and data sharing.

Association Between Alcohol Use and Primary Open Angle Glaucoma.

In the diverse All of Us database, there was a dose-response relationship between alcohol consumption and POAG risk, which was more pronounced in female participants.

Social Factors Associated with the Risk of Glaucoma Suspect Conversion to Glaucoma: Analysis of the Nationwide All of Us Program.

Several social factors were associated with the conversion from GS to OAG, which may help to identify patients at higher risk of disease progression.

PyOPV: An Open-Source Python Package for Ophthalmic Visual Field Data Management.

PyOPV provides an efficient solution for handling ophthalmic visual field data, bridging a critical gap in data interoperability and research scalability.

Assessment of Missing Data on Glaucoma Severity Among Participants in the NIH All of Us Research Program of the United States.

There were significant differences between glaucoma participants with glaucoma severity stage specified versus those with unstaged disease across multiple socioeconomic characteristics and self-reported barriers to care.

Associations Between Physical Activity and Glaucoma: Analysis of the National Institutes of Health All of Us Research Program.

There were no definitive associations between physical activity and primary open angle glaucoma diagnosis among All of Us participants, which was replicated among age-stratified subgroup analyses.

Association between metformin use with circumpapillary retinal nerve fibre layer thickness and capillary vessel density in glaucoma.

Metformin use was associated with higher wiCD and thicker cpRNFL.