Pieter W. M. Bonnemaijer

Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population.

In addition to previously described determinants such as age and refraction, we found that systemic vascular and neurovascular diseases were associated with reduced pRNFLT.

Differences in clinical presentation of primary open-angle glaucoma between African and European populations.

In this multi-ethnic comparative study, Sub-Saharan Africans present at a younger age with lower visual acuity, higher IOP, larger VCDR, than SAC and Dutch participants.

Genetic African Ancestry Is Associated With Central Corneal Thickness and Intraocular Pressure in Primary Open-Angle Glaucoma.

This study demonstrated that a higher proportion of GAA was associated with a thinner CCT and a higher IOP in POAG patients.

Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma.

Using two complementary approaches we found no evidence to support a genetic overlap between myopia and POAG; our results suggest that the comorbidity of these diseases is not influenced by common variants.

Performance of Polygenic Risk Scores for Primary Open-Angle Glaucoma in Populations of African Descent.

In this cross-sectional study, despite some improvements in OR-based risk stratification using the Gharahkhani PRSs, Han PRSs, and Craig PRSs, consistently lower improvements in AUROC and R2 for African-ancestry compared with European-ancestry groups highlight the…