Brenner Lena

Structural and Functional Progression in the Early Manifest Glaucoma Trial.

In eyes with manifest glaucoma, progression in the visual field was detected first more than 4 times as often as progression in the optic disc.

Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up.

Our results support the widespread, albeit arbitrary, use of a better-eye visual field of <50% as an important threshold for a significant reduction in VRQOL.